Piracetam (2-oxo-1-pyrrolidineacetamide)

Piracetam (2-oxo-1-pyrrolidineacetamide) is a derivative of the neurotransmitter GABA (Gamma Amino Butyric Acid). Interestingly it is chemically related to the amino acid Pyroglutamic Acid (Pyrrolidine Carboxylic acid), which occurs in cerebrospinal fluid and plays an important role in cognitive functioning.

Piracetam positively supports healthy cognitive & cardiovascular functioning by a multifaceted means of action.

Piracetam has these effects on the brain:

• Enhances Brain Metabolism (By increasing Glucose Utilization, Blood & Oxygen Flow) [Boosts mental energy & cerebral circulation].
• Increases Cerebral Phospholipids & Cellular Membrane Fluidity (By interacting with the polar head moieties of the phospholipid bilayer) [Supports healthy neuron communication & structure].
• Supports Cognitive Receptors (By amplifying the density of the Muscarinic Cholinergic [Frontal Cortex, Striatum, & Hippocampus], NMDA (NMethylDAspartate) [Hippocampus], & AMPA (Alphaamino3hydroxy5Methyl4isoxazolePropionic Acid) [Cerebral Cortex] Receptors) [Strengthens neurotransmitter receptors involved in memory and neuroprotection].
• Stimulates the Corpus Callosum, an area of the brain that controls communication between the left and right hemispheres (Increases communication between both hemispheres) [Involved in speech and creative thinking].
• Stimulates the Locus Coeruleus, (specialized neurons) [Involved in information processing, attention, cortical/behavioral arousal, learning and memory]
• Inhibits Platelet Aggregation (By increasing RedWhite blood cells & Platelet deformability, inhibiting thromboxane A2 synthetase or antagonism of thromboxane A2, reducing von Willebrand's factor & fibrinogen levels) [Supports Healthy Blood Flow].
• Decreases EEG complexity (Increases cooperatively of brain functional processing) [Positively effects NeuroElectrical Functioning].
• Has a significant antioxidant effect.

Piracetam has been approved & used since 1970's worldwide (Europe, Asia, and South American) for various health conditions. Recommended by many healthcare professionals and health organizations, such as the Life Extension Foundation, as a Nootropic.

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