Graviola (Annona Muricata)
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"Derived from a tree in the rain forests of Africa, South America, and Southeast Asia. The bark, leaves, root, and fruits have been used as traditional remedies in many countries. Extracts of graviola have been shown to have antiviral (1), antiparasitic, antirheumatic, astringent, emetic (2), antileishmanial and cytotoxic (3) (4) effects. Graviola has also been shown to be effective against multidrug resistant cancer cells line (5) (4). There are no large scale studies in humans on the effects of graviola. Alkaloids extracted from graviola may cause neuronal dysfunction and degeneration leading to symptoms reminiscent of Parkinson's Disease(6)."
–From the Memorial Sloan-Kettering Cancer Center (mskcc.org)
NRx Graviola Extract is the most potent on the market today. Meticulously
extracted to a 10:1 extract. Each capsule contains an equivalent to 5000mg of
Graviola leaf and stem.
- Padma P, Pramod NP, Thyagarajan SP, Khosa RL. Effect of the extract of Annona muricata and Petunia nyctaginiflora on Herpes simplex virus. J Ethnopharmacol. 1998;61:81-3.
- dos Santos AF,.Sant'Ana AE. Molluscicidal properties of some species of Annona. Phytomedicine. 2001;8:115-20.
- Jaramillo MC, Arango GJ, Gonzalez MC, Robledo SM, Velez ID. Cytotoxicity and antileishmanial activity of Annona muricata pericarp. Fitoterapia 2000;71:183-6.
- Liaw CC, Chang FR, Lin CY, Chou CJ, Chiu HF, Wu MJ et al. New cytotoxic monotetrahydrofuran annonaceous acetogenins from Annona muricata. J Nat.Prod. 2002;65:470-5.
- Oberlies NH, Chang CJ, McLaughlin JL. Structure-activity relationships of diverse Annonaceous acetogenins against multidrug resistant human mammary adenocarcinoma (MCF-7/Adr) cells. J Med Chem. 1997;40:2102-6.
- Lannuzel A, Michel PP, Caparros-Lefebvre D, Abaul J, Hocquemiller R, Ruberg M.Toxicity of Annonaceae for dopaminergic neurons: potential role in atypical parkinsonism in Guadeloupe. Mov Disord. 2002;17:84-90.